Microencapsulation of Insulin Microcrystals

Human insulin microcrystals with lactose carriers for pulmonary delivery.

Dry powder formulations for pulmonary delivery are attractive because many issues of solubility and stability can be minimized. Human insulin microcrystals with lactose carriers were produced for pulmonary delivery. The average particle diameter was 2.3 microm, with a narrow, monodispersed size distribution. The percentages of high molecular weight proteins (%HMWPs), other insulin-related compo...

Microencapsulation of Cells

................................................................................................. 2 Introduction Hormone replacement............................................................................ 3 Encapsulation of cells........................................................................ 4 Problem statement...........................................................................

Characterization of insulin microcrystals using powder diffraction and multivariate data analysis

Twelve different microcrystalline insulin formulations were investigated by X-ray powder diffraction and were shown to have very characteristic patterns. Three of the formulations crystallize in the same crystal system, but have structural differences in the N-terminal B-chain of the insulin molecule. This difference was efficiently detected in the powder patterns. The sensitivity of the method...

Microencapsulation of Rodenticides

Microencapsulation of Vitamins

Functional foods are beginning to play a major role in what consumers buy and eat. The International Life Science Institute has defined a functional food as ‘a food which has a beneficial effect on one or more target functions of the body, above and beyond the usual effects of food, such as improving the state of health and well-being or reducing the risk of disease. Examples of these types of ...